Pathology EMQ template.

Name: Timothy Peplow

Candidate number:

Theme: Thyroid

 

OPTION LIST

 

AAnaplastic carcinomaBFollicular carcinomaCHürthle cell carcinoma   DLymphomaEMedullary cell carcinomaFPapillary carcinomaGSpindle cell tumour   HSquamous cell carcinoma 

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

 

1. A differentiated carcinoma that is derived from the thyroid epithelium, can be associated with the RET proto-oncogene, and is the most common thyroid malignancy.

 

2. This malignancy arises from the C cells of the thyroid, and is often associated with MEN2. Carcinoembryonic antigen (CEA) can be used as a tumour marker for this malignancy.

 

3. This malignancy is undifferentiated and displays aggressive behaviour with very poor prognosis.

 

4. This rare malignancy has a high tendency to metastasise to lung and bone with local lymph node involvement. Histology shows pink-staining enlarged epithelial cells.

 

5. Thyroglobulin can be used as a tumour marker for this common thyroid malignancy, which has a tendency to metastasise to the lungs and bone with no local lymph node involvement. It is more common in females than males.

 

ANSWERS

1. F2. E3. A4. C5. B